WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_GTGACGY_V$E4F1_Q6       ID:DB_ID:2412
C=646; O=9; E=1.60; R=5.62; rawP=3.50e-05; adjP=0.0051
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100483 NA METTL21D methyltransferase like 21D 79609 ENSG00000100483
2  ENSG00000109046 NA WSB1 WD repeat and SOCS box containing 1 26118 ENSG00000109046
3  ENSG00000133114 NA KIAA1704 KIAA1704 55425 ENSG00000133114
4  ENSG00000077458 NA FAM76B family with sequence similarity 76, member B 143684 ENSG00000077458
5  ENSG00000100650 NA SRSF5 serine/arginine-rich splicing factor 5 6430 ENSG00000100650
6  ENSG00000132141 NA CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 10693 ENSG00000132141
7  ENSG00000135164 NA DMTF1 cyclin D binding myb-like transcription factor 1 9988 ENSG00000135164
8  ENSG00000110697 NA PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 9600 ENSG00000110697
9  ENSG00000120798 NA NR2C1 nuclear receptor subfamily 2, group C, member 1 7181 ENSG00000120798


Database:Transcription Target       Name:hsa_RCGCANGCGY_V$NRF1_Q6       ID:DB_ID:2441
C=894; O=9; E=2.22; R=4.06; rawP=0.0004; adjP=0.0292
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000066651 NA TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 60487 ENSG00000066651
2  ENSG00000164073 NA MFSD8 major facilitator superfamily domain containing 8 256471 ENSG00000164073
3  ENSG00000132716 NA DCAF8 DDB1 and CUL4 associated factor 8 50717 ENSG00000132716 ENSG00000258465
4  ENSG00000099622 NA CIRBP cold inducible RNA binding protein 1153 ENSG00000099622
5  ENSG00000120699 NA EXOSC8 exosome component 8 11340 ENSG00000120699
6  ENSG00000174839 NA FAM116A family with sequence similarity 116, member A 201627 ENSG00000174839
7  ENSG00000176401 NA EID2B EP300 interacting inhibitor of differentiation 2B 126272 ENSG00000176401
8  ENSG00000133111 NA RFXAP regulatory factor X-associated protein 5994 ENSG00000133111
9  ENSG00000120798 NA NR2C1 nuclear receptor subfamily 2, group C, member 1 7181 ENSG00000120798


Database:Transcription Target       Name:hsa_TMTCGCGANR_UNKNOWN       ID:DB_ID:2370
C=158; O=4; E=0.39; R=10.20; rawP=0.0007; adjP=0.0341
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137504 NA CREBZF CREB/ATF bZIP transcription factor 58487 ENSG00000137504
2  ENSG00000100650 NA SRSF5 serine/arginine-rich splicing factor 5 6430 ENSG00000100650
3  ENSG00000163728 NA TTC14 tetratricopeptide repeat domain 14 151613 ENSG00000163728
4  ENSG00000146856 NA AGBL3 ATP/GTP binding protein-like 3 340351 ENSG00000146856


Database:Transcription Target       Name:hsa_V$AHRARNT_01       ID:DB_ID:2010
C=137; O=3; E=0.34; R=8.83; rawP=0.0049; adjP=0.1201
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137504 NA CREBZF CREB/ATF bZIP transcription factor 58487 ENSG00000137504
2  ENSG00000108848 NA LUC7L3 LUC7-like 3 (S. cerevisiae) 51747 ENSG00000108848
3  ENSG00000109046 NA WSB1 WD repeat and SOCS box containing 1 26118 ENSG00000109046


Database:Transcription Target       Name:hsa_SMTTTTGT_UNKNOWN       ID:DB_ID:2358
C=399; O=4; E=0.99; R=4.04; rawP=0.0177; adjP=0.1201
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000258890 NA CEP95 centrosomal protein 95kDa 90799 ENSG00000258890
2  ENSG00000100650 NA SRSF5 serine/arginine-rich splicing factor 5 6430 ENSG00000100650
3  ENSG00000100483 NA METTL21D methyltransferase like 21D 79609 ENSG00000100483
4  ENSG00000108848 NA LUC7L3 LUC7-like 3 (S. cerevisiae) 51747 ENSG00000108848


Database:Transcription Target       Name:hsa_V$HNF1_C       ID:DB_ID:1991
C=240; O=3; E=0.60; R=5.04; rawP=0.0221; adjP=0.1201
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100483 NA METTL21D methyltransferase like 21D 79609 ENSG00000100483
2  ENSG00000108848 NA LUC7L3 LUC7-like 3 (S. cerevisiae) 51747 ENSG00000108848
3  ENSG00000204444 NA APOM apolipoprotein M 55937 ENSG00000204444


Database:Transcription Target       Name:hsa_V$PPAR_DR1_Q2       ID:DB_ID:2248
C=257; O=3; E=0.64; R=4.70; rawP=0.0264; adjP=0.1201
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000175455 NA CCDC14 coiled-coil domain containing 14 64770 ENSG00000175455
2  ENSG00000120798 NA NR2C1 nuclear receptor subfamily 2, group C, member 1 7181 ENSG00000120798
3  ENSG00000009724 NA MASP2 mannan-binding lectin serine peptidase 2 10747 ENSG00000009724


Database:Transcription Target       Name:hsa_GCCATNTTG_V$YY1_Q6       ID:DB_ID:2459
C=419; O=4; E=1.04; R=3.85; rawP=0.0207; adjP=0.1201
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100650 NA SRSF5 serine/arginine-rich splicing factor 5 6430 ENSG00000100650
2  ENSG00000108848 NA LUC7L3 LUC7-like 3 (S. cerevisiae) 51747 ENSG00000108848
3  ENSG00000165819 NA METTL3 methyltransferase like 3 56339 ENSG00000165819
4  ENSG00000109046 NA WSB1 WD repeat and SOCS box containing 1 26118 ENSG00000109046


Database:Transcription Target       Name:hsa_V$ELK1_01       ID:DB_ID:1853
C=266; O=3; E=0.66; R=4.55; rawP=0.0288; adjP=0.1201
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137504 NA CREBZF CREB/ATF bZIP transcription factor 58487 ENSG00000137504
2  ENSG00000132485 NA ZRANB2 zinc finger, RAN-binding domain containing 2 9406 ENSG00000132485
3  ENSG00000135164 NA DMTF1 cyclin D binding myb-like transcription factor 1 9988 ENSG00000135164


Database:Transcription Target       Name:hsa_SCGGAAGY_V$ELK1_02       ID:DB_ID:2413
C=1176; O=7; E=2.92; R=2.40; rawP=0.0274; adjP=0.1201
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137504 NA CREBZF CREB/ATF bZIP transcription factor 58487 ENSG00000137504
2  ENSG00000132485 NA ZRANB2 zinc finger, RAN-binding domain containing 2 9406 ENSG00000132485
3  ENSG00000258890 NA CEP95 centrosomal protein 95kDa 90799 ENSG00000258890
4  ENSG00000185019 NA UBOX5 U-box domain containing 5 22888 ENSG00000185019
5  ENSG00000163728 NA TTC14 tetratricopeptide repeat domain 14 151613 ENSG00000163728
6  ENSG00000155636 NA RBM45 RNA binding motif protein 45 129831 ENSG00000155636
7  ENSG00000198625 NA MDM4 Mdm4 p53 binding protein homolog (mouse) 4194 ENSG00000198625




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).